SubtiBank SubtiBank
spoVT [2018-02-10T12:07:42.000Z]
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spoVT [2018-02-10T12:07:42.000Z]

transcription activator and repressor of SigG-dependent genes
locus
BSU00560
pI
4.68
mw
19.60 kDa
protein length
178 aa Sequence Blast
gene length
534 bp Sequence Blast
function
regulation of forespore gene expression
product
transcriptional regulator
essential
no
synonyms
yabL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

    • Gene

    Coordinates
    64,099 → 64,635

    The protein

    Paralogous protein(s)

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB], [protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|Abh] (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)

    • Structure

  • [PDB|2W1R] (full-length), [PDB|2W1T] (C-terminal domain) [PDB|2RO5] (recognition domain)

    • [SW|Localization]

  • Cytoplasm (Homogeneous) [Pubmed|16479537]

    • Expression and Regulation

    Operons

    genes
    [gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
    description
    [Pubmed|8755877]

    sigma factors

  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, [Pubmed|15699190], in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon]
  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|15699190,8755877], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]

    • regulation

  • expressed in the forespore ([protein|search|SigG]) [Pubmed|8755877]
    • view in new tab

    genes
    [gene|C595D32D98723E93AF26B5C864FD61AF4739E069|fin]-[gene|AD1F39823ABCE2A222259B879513752942C59590|mfd]-[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
    description
    [pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • BKE00560 (Δ[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC
  • BKK00560 (Δ[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC

    • References

  • 16497325,18996130,15063493,8755877,16479537,16159768,22522895,15980461,27790204